to prevent (someone or something) from dealing with or experiencing something : to keep (someone or something) separate from something unpleasant, dangerous, etc.隔离;隔绝;使免受(不良影响等)

The company has tried to insulate itself from the region’s political turmoil.
这家公司试图使自身免受本地区政治动乱的影响。
I wish I could insulate my children from/against painful experiences.
我希望能使我的孩子们免遭痛苦。